Dissemination and genome characterization of a human adenovirus F41 in a patient with B-Cell lymphoma

Adenovirus (HAdV) F41 is a common cause of gastroenteritis and has rarely been reported associated with disseminated disease. In this report, an adult patient with a history of ulcerative colitis, cryptogenic cirrhosis, stage III adenocarcinoma, high-grade diffuse large B-cell lymphoma on chemothera...

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Autores principales: Fall, Amary, Campodónico, Victoria L., Howard, Craig, Gallagher, Nicholas, Bailey, Gabrielle, Kajon, Adriana E., Mostafa, Heba H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327306/
https://www.ncbi.nlm.nih.gov/pubmed/37415207
http://dx.doi.org/10.1186/s12985-023-02101-3
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author Fall, Amary
Campodónico, Victoria L.
Howard, Craig
Gallagher, Nicholas
Bailey, Gabrielle
Kajon, Adriana E.
Mostafa, Heba H.
author_facet Fall, Amary
Campodónico, Victoria L.
Howard, Craig
Gallagher, Nicholas
Bailey, Gabrielle
Kajon, Adriana E.
Mostafa, Heba H.
author_sort Fall, Amary
collection PubMed
description Adenovirus (HAdV) F41 is a common cause of gastroenteritis and has rarely been reported associated with disseminated disease. In this report, an adult patient with a history of ulcerative colitis, cryptogenic cirrhosis, stage III adenocarcinoma, high-grade diffuse large B-cell lymphoma on chemotherapy was diagnosed with disseminated adenovirus infection. HAdV DNA was quantified in stool, plasma, and urine with viral loads of 7, 4, and 3 log10 copies/mL, respectively. The patient’s course was rapidly progressive and he passed away 2 days after initiation of antiviral therapy. The patient’s infecting virus was characterized as HAdV-F41 by whole genome sequencing.
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spelling pubmed-103273062023-07-08 Dissemination and genome characterization of a human adenovirus F41 in a patient with B-Cell lymphoma Fall, Amary Campodónico, Victoria L. Howard, Craig Gallagher, Nicholas Bailey, Gabrielle Kajon, Adriana E. Mostafa, Heba H. Virol J Case Report Adenovirus (HAdV) F41 is a common cause of gastroenteritis and has rarely been reported associated with disseminated disease. In this report, an adult patient with a history of ulcerative colitis, cryptogenic cirrhosis, stage III adenocarcinoma, high-grade diffuse large B-cell lymphoma on chemotherapy was diagnosed with disseminated adenovirus infection. HAdV DNA was quantified in stool, plasma, and urine with viral loads of 7, 4, and 3 log10 copies/mL, respectively. The patient’s course was rapidly progressive and he passed away 2 days after initiation of antiviral therapy. The patient’s infecting virus was characterized as HAdV-F41 by whole genome sequencing. BioMed Central 2023-07-06 /pmc/articles/PMC10327306/ /pubmed/37415207 http://dx.doi.org/10.1186/s12985-023-02101-3 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Fall, Amary
Campodónico, Victoria L.
Howard, Craig
Gallagher, Nicholas
Bailey, Gabrielle
Kajon, Adriana E.
Mostafa, Heba H.
Dissemination and genome characterization of a human adenovirus F41 in a patient with B-Cell lymphoma
title Dissemination and genome characterization of a human adenovirus F41 in a patient with B-Cell lymphoma
title_full Dissemination and genome characterization of a human adenovirus F41 in a patient with B-Cell lymphoma
title_fullStr Dissemination and genome characterization of a human adenovirus F41 in a patient with B-Cell lymphoma
title_full_unstemmed Dissemination and genome characterization of a human adenovirus F41 in a patient with B-Cell lymphoma
title_short Dissemination and genome characterization of a human adenovirus F41 in a patient with B-Cell lymphoma
title_sort dissemination and genome characterization of a human adenovirus f41 in a patient with b-cell lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327306/
https://www.ncbi.nlm.nih.gov/pubmed/37415207
http://dx.doi.org/10.1186/s12985-023-02101-3
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