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Aberrant mechanical loading induces annulus fibrosus cells apoptosis in intervertebral disc degeneration via mechanosensitive ion channel Piezo1

BACKGROUND: Intervertebral disc degeneration (IVDD) is closely associated with the structural damage in the annulus fibrosus (AF). Aberrant mechanical loading is an important inducement of annulus fibrosus cells (AFCs) apoptosis, which contributes to the AF structural damage and aggravates IVDD, but...

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Detalles Bibliográficos
Autores principales:	Liu, Chenhao, Gao, Xiaoxin, Lou, Jinhui, Li, Haiyin, Chen, Yuxuan, Chen, Molong, Zhang, Yuyao, Hu, Zhilei, Chang, Xian, Luo, Menglin, Zhai, Yu, Li, Changqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327399/ https://www.ncbi.nlm.nih.gov/pubmed/37420255 http://dx.doi.org/10.1186/s13075-023-03093-9

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