A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment?

We report the case of a patient with chronic granulomatous disease and acne treated with isotretinoin, who developed a diffuse staphylococcal skin infection during the therapy. Chronic granulomatous disease is a rare genetic disorder characterized by an altered innate immunity with an increased risk...

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Autores principales: Brusasco, Marco, Feliciani, Claudio, de Felici del Giudice, Maria Beatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327657/
https://www.ncbi.nlm.nih.gov/pubmed/37426369
http://dx.doi.org/10.4081/dr.2023.9631
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author Brusasco, Marco
Feliciani, Claudio
de Felici del Giudice, Maria Beatrice
author_facet Brusasco, Marco
Feliciani, Claudio
de Felici del Giudice, Maria Beatrice
author_sort Brusasco, Marco
collection PubMed
description We report the case of a patient with chronic granulomatous disease and acne treated with isotretinoin, who developed a diffuse staphylococcal skin infection during the therapy. Chronic granulomatous disease is a rare genetic disorder characterized by an altered innate immunity with an increased risk of potentially lethal bacterial and fungal infections. Although chronic granulomatous disease is rare, acne is a common manifestation in these patients, but there are no data about the gold standard therapy.
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spelling pubmed-103276572023-07-08 A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment? Brusasco, Marco Feliciani, Claudio de Felici del Giudice, Maria Beatrice Dermatol Reports Case Report We report the case of a patient with chronic granulomatous disease and acne treated with isotretinoin, who developed a diffuse staphylococcal skin infection during the therapy. Chronic granulomatous disease is a rare genetic disorder characterized by an altered innate immunity with an increased risk of potentially lethal bacterial and fungal infections. Although chronic granulomatous disease is rare, acne is a common manifestation in these patients, but there are no data about the gold standard therapy. PAGEPress Publications, Pavia, Italy 2022-12-29 /pmc/articles/PMC10327657/ /pubmed/37426369 http://dx.doi.org/10.4081/dr.2023.9631 Text en ©Copyright: the Author(s) https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (by-nc 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Case Report
Brusasco, Marco
Feliciani, Claudio
de Felici del Giudice, Maria Beatrice
A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment?
title A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment?
title_full A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment?
title_fullStr A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment?
title_full_unstemmed A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment?
title_short A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment?
title_sort case of chronic granulomatous disease and acne: is isotretinoin a safe treatment?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327657/
https://www.ncbi.nlm.nih.gov/pubmed/37426369
http://dx.doi.org/10.4081/dr.2023.9631
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