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SRSF3 shapes the structure of miR‐17‐92 cluster RNA and promotes selective processing of miR‐17 and miR‐20a

MicroRNA (miRNA) biogenesis is tightly regulated to maintain distinct miRNA expression patterns. Almost half of mammalian miRNAs are generated from miRNA clusters, but this process is not well understood. We show here that Serine‐arginine rich splicing factor 3 (SRSF3) controls the processing of miR...

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Detalles Bibliográficos
Autores principales: Ratnadiwakara, Madara, Bahrudeen, Mohamed NM, Aikio, Erika, Takabe, Piia, Engel, Rebekah M, Zahir, Zileena, Jardé, Thierry, McMurrick, Paul J, Abud, Helen E, Änkö, Minna‐Liisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328067/
https://www.ncbi.nlm.nih.gov/pubmed/37306233
http://dx.doi.org/10.15252/embr.202256021