Cargando…
Anesthetic Management of a Patient With McArdle Disease: A Case Report and Review of the Literature
McArdle disease (glycogen storage disorder type V) is a rare inherited condition resulting in impaired energy metabolism. Challenges in anesthetized patients with McArdle disease include hypoglycemia, rhabdomyolysis, myoglobinuria, acute renal failure, and postoperative fatigue. We review the litera...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328145/ https://www.ncbi.nlm.nih.gov/pubmed/37425602 http://dx.doi.org/10.7759/cureus.40092 |
_version_ | 1785069736495677440 |
---|---|
author | Kotha, Rohini Jones, Anastasia Girgenti, Gregory T Nahrwold, Daniel A |
author_facet | Kotha, Rohini Jones, Anastasia Girgenti, Gregory T Nahrwold, Daniel A |
author_sort | Kotha, Rohini |
collection | PubMed |
description | McArdle disease (glycogen storage disorder type V) is a rare inherited condition resulting in impaired energy metabolism. Challenges in anesthetized patients with McArdle disease include hypoglycemia, rhabdomyolysis, myoglobinuria, acute renal failure, and postoperative fatigue. We review the literature and discuss a successful anesthetic that had no perioperative complications for a patient with McArdle disease undergoing robotic-assisted lung wedge resection. Preoperatively, we obtained a complete blood count, chemistry panel, and creatine kinase level. Intraoperatively, we proceeded with general endotracheal anesthesia and monitored point-of-care electrolytes, hemoglobin, and blood glucose. The patient had an uneventful postoperative recovery and was discharged home on postoperative Day 3. Patients with McArdle disease can undergo safe surgery with appropriate perioperative planning and a well-managed anesthetic. Efforts should focus on mitigating the risks of hypoglycemia, rhabdomyolysis, myoglobinuria, acute renal failure, and postoperative fatigue. |
format | Online Article Text |
id | pubmed-10328145 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-103281452023-07-08 Anesthetic Management of a Patient With McArdle Disease: A Case Report and Review of the Literature Kotha, Rohini Jones, Anastasia Girgenti, Gregory T Nahrwold, Daniel A Cureus Anesthesiology McArdle disease (glycogen storage disorder type V) is a rare inherited condition resulting in impaired energy metabolism. Challenges in anesthetized patients with McArdle disease include hypoglycemia, rhabdomyolysis, myoglobinuria, acute renal failure, and postoperative fatigue. We review the literature and discuss a successful anesthetic that had no perioperative complications for a patient with McArdle disease undergoing robotic-assisted lung wedge resection. Preoperatively, we obtained a complete blood count, chemistry panel, and creatine kinase level. Intraoperatively, we proceeded with general endotracheal anesthesia and monitored point-of-care electrolytes, hemoglobin, and blood glucose. The patient had an uneventful postoperative recovery and was discharged home on postoperative Day 3. Patients with McArdle disease can undergo safe surgery with appropriate perioperative planning and a well-managed anesthetic. Efforts should focus on mitigating the risks of hypoglycemia, rhabdomyolysis, myoglobinuria, acute renal failure, and postoperative fatigue. Cureus 2023-06-07 /pmc/articles/PMC10328145/ /pubmed/37425602 http://dx.doi.org/10.7759/cureus.40092 Text en Copyright © 2023, Kotha et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Anesthesiology Kotha, Rohini Jones, Anastasia Girgenti, Gregory T Nahrwold, Daniel A Anesthetic Management of a Patient With McArdle Disease: A Case Report and Review of the Literature |
title | Anesthetic Management of a Patient With McArdle Disease: A Case Report and Review of the Literature |
title_full | Anesthetic Management of a Patient With McArdle Disease: A Case Report and Review of the Literature |
title_fullStr | Anesthetic Management of a Patient With McArdle Disease: A Case Report and Review of the Literature |
title_full_unstemmed | Anesthetic Management of a Patient With McArdle Disease: A Case Report and Review of the Literature |
title_short | Anesthetic Management of a Patient With McArdle Disease: A Case Report and Review of the Literature |
title_sort | anesthetic management of a patient with mcardle disease: a case report and review of the literature |
topic | Anesthesiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328145/ https://www.ncbi.nlm.nih.gov/pubmed/37425602 http://dx.doi.org/10.7759/cureus.40092 |
work_keys_str_mv | AT kotharohini anestheticmanagementofapatientwithmcardlediseaseacasereportandreviewoftheliterature AT jonesanastasia anestheticmanagementofapatientwithmcardlediseaseacasereportandreviewoftheliterature AT girgentigregoryt anestheticmanagementofapatientwithmcardlediseaseacasereportandreviewoftheliterature AT nahrwolddaniela anestheticmanagementofapatientwithmcardlediseaseacasereportandreviewoftheliterature |