Repurposing the Medicines for Malaria Venture’s COVID Box to discover potent inhibitors of Toxoplasma gondii, and in vivo efficacy evaluation of almitrine bismesylate (MMV1804175) in chronically infected mice

Toxoplasmosis, caused by the obligate intracellular parasite Toxoplasma gondii, affects about one-third of the world’s population and can cause severe congenital, neurological and ocular issues. Current treatment options are limited, and there are no human vaccines available to prevent transmission....

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Detalles Bibliográficos
Autores principales: dos Santos, Bruna Ramos, Ramos, Amanda Bruno da Silva Bellini, de Menezes, Renata Priscila Barros, Scotti, Marcus Tullius, Colombo, Fábio Antônio, Marques, Marcos José, Reimão, Juliana Quero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328330/
https://www.ncbi.nlm.nih.gov/pubmed/37418497
http://dx.doi.org/10.1371/journal.pone.0288335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328330/
https://www.ncbi.nlm.nih.gov/pubmed/37418497
http://dx.doi.org/10.1371/journal.pone.0288335

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