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Single-cell and spatial transcriptomics identify a macrophage population associated with skeletal muscle fibrosis
Macrophages are essential for skeletal muscle homeostasis, but how their dysregulation contributes to the development of fibrosis in muscle disease remains unclear. Here, we used single-cell transcriptomics to determine the molecular attributes of dystrophic and healthy muscle macrophages. We identi...
Autores principales: | Coulis, Gerald, Jaime, Diego, Guerrero-Juarez, Christian, Kastenschmidt, Jenna M., Farahat, Philip K., Nguyen, Quy, Pervolarakis, Nicholas, McLinden, Katherine, Thurlow, Lauren, Movahedi, Saba, Hughes, Brandon S., Duarte, Jorge, Sorn, Andrew, Montoya, Elizabeth, Mozaffar, Izza, Dragan, Morgan, Othy, Shivashankar, Joshi, Trupti, Hans, Chetan P., Kimonis, Virginia, MacLean, Adam L., Nie, Qing, Wallace, Lindsay M., Harper, Scott Q., Mozaffar, Tahseen, Hogarth, Marshall W., Bhattacharya, Surajit, Jaiswal, Jyoti K., Golann, David R., Su, Qi, Kessenbrock, Kai, Stec, Michael, Spencer, Melissa J., Zamudio, Jesse R., Villalta, S. Armando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328414/ https://www.ncbi.nlm.nih.gov/pubmed/37418531 http://dx.doi.org/10.1126/sciadv.add9984 |
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