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Loss of the extracellular matrix protein Perlecan disrupts axonal and synaptic stability during Drosophila development

Heparan sulfate proteoglycans (HSPGs) form essential components of the extracellular matrix (ECM) and basement membrane (BM) and have both structural and signaling roles. Perlecan is a secreted ECM-localized HSPG that contributes to tissue integrity and cell-cell communication. Although a core compo...

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Detalles Bibliográficos
Autores principales:	Guss, Ellen J, Akbergenova, Yulia, Cunningham, Karen L, Littleton, J Troy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2023
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328508/ https://www.ncbi.nlm.nih.gov/pubmed/37368474 http://dx.doi.org/10.7554/eLife.88273

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