From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions

In the progressive phase of multiple sclerosis (MS), the hampered differentiation capacity of oligodendrocyte precursor cells (OPCs) eventually results in remyelination failure. We have previously shown that DNA methylation of Id2/Id4 is highly involved in OPC differentiation and remyelination. In t...

Descripción completa

Detalles Bibliográficos
Autores principales: Tiane, Assia, Schepers, Melissa, Reijnders, Rick A., van Veggel, Lieve, Chenine, Sarah, Rombaut, Ben, Dempster, Emma, Verfaillie, Catherine, Wasner, Kobi, Grünewald, Anne, Prickaerts, Jos, Pishva, Ehsan, Hellings, Niels, van den Hove, Daniel, Vanmierlo, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328906/
https://www.ncbi.nlm.nih.gov/pubmed/37286732
http://dx.doi.org/10.1007/s00401-023-02596-8

Ejemplares similares

Ejemplares similares