A novel CTLA-4 blocking strategy based on nanobody enhances the activity of dendritic cell vaccine-stimulated antitumor cytotoxic T lymphocytes

Despite the great success of CTLA-4 blocking in cancer treatment, the use of anti-CTLA-4 monoclonal antibodies still faces many limitations. Now, immune checkpoint blocking coupled with adoptive cell therapy is gaining much attention. In this paper, we reported a strategy on the basis of anti-CTLA-4...

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Detalles Bibliográficos
Autores principales: Yang, Wenli, Pang, Yanyang, Wang, Xi, Lai, Zhiheng, Lu, Yanda, Zheng, Shaojiang, Wang, Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328924/
https://www.ncbi.nlm.nih.gov/pubmed/37419930
http://dx.doi.org/10.1038/s41419-023-05914-w

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