Structural insights into RNA bridging between HIV-1 Vif and antiviral factor APOBEC3G

Great effort has been devoted to discovering the basis of A3G-Vif interaction, the key event of HIV’s counteraction mechanism to evade antiviral innate immune response. Here we show reconstitution of the A3G-Vif complex and subsequent A3G ubiquitination in vitro and report the cryo-EM structure of t...

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Detalles Bibliográficos
Autores principales: Kouno, Takahide, Shibata, Satoshi, Shigematsu, Megumi, Hyun, Jaekyung, Kim, Tae Gyun, Matsuo, Hiroshi, Wolf, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328928/
https://www.ncbi.nlm.nih.gov/pubmed/37419875
http://dx.doi.org/10.1038/s41467-023-39796-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328928/
https://www.ncbi.nlm.nih.gov/pubmed/37419875
http://dx.doi.org/10.1038/s41467-023-39796-5

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