Cargando…
Structural insights into RNA bridging between HIV-1 Vif and antiviral factor APOBEC3G
Great effort has been devoted to discovering the basis of A3G-Vif interaction, the key event of HIV’s counteraction mechanism to evade antiviral innate immune response. Here we show reconstitution of the A3G-Vif complex and subsequent A3G ubiquitination in vitro and report the cryo-EM structure of t...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328928/ https://www.ncbi.nlm.nih.gov/pubmed/37419875 http://dx.doi.org/10.1038/s41467-023-39796-5 |