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Elevated glutamate impedes anti-HIV-1 CD8 + T cell responses in HIV-1-infected individuals on antiretroviral therapy

CD8 + T cells are essential for long-lasting HIV-1 control and have been harnessed to develop therapeutic and preventive approaches for people living with HIV-1 (PLWH). HIV-1 infection induces marked metabolic alterations. However, it is unclear whether these changes affect the anti-HIV function of...

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Detalles Bibliográficos
Autores principales: Wang, You-Yuan, Zhen, Cheng, Hu, Wei, Huang, Hui-Huang, Li, Yan-Jun, Zhou, Ming-Ju, Li, Jing, Fu, Yu-Long, Zhang, Peng, Li, Xiao-Yu, Yang, Tao, Song, Jin-Wen, Fan, Xing, Zou, Jun, Meng, Si-Run, Qin, Ya-Qin, Jiao, Yan-Mei, Xu, Ruonan, Zhang, Ji-Yuan, Zhou, Chun-Bao, Yuan, Jin-Hong, Huang, Lei, Shi, Ming, Cheng, Liang, Wang, Fu-Sheng, Zhang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328948/
https://www.ncbi.nlm.nih.gov/pubmed/37419968
http://dx.doi.org/10.1038/s42003-023-04975-z

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