Signatures of V(H)1-69-derived hepatitis C virus neutralizing antibody precursors defined by binding to envelope glycoproteins

An effective preventive vaccine for hepatitis C virus (HCV) remains a major unmet need. Antigenic region 3 (AR3) on the E1E2 envelope glycoprotein complex overlaps with the CD81 receptor binding site and represents an important epitope for broadly neutralizing antibodies (bNAbs) and is therefore imp...

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Detalles Bibliográficos
Autores principales: Capella-Pujol, Joan, de Gast, Marlon, Radić, Laura, Zon, Ian, Chumbe, Ana, Koekkoek, Sylvie, Olijhoek, Wouter, Schinkel, Janke, van Gils, Marit J., Sanders, Rogier W., Sliepen, Kwinten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328973/
https://www.ncbi.nlm.nih.gov/pubmed/37419906
http://dx.doi.org/10.1038/s41467-023-39690-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328973/
https://www.ncbi.nlm.nih.gov/pubmed/37419906
http://dx.doi.org/10.1038/s41467-023-39690-0

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