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Early Repolarization Augmentation Mimicking Pseudo-Infarction in a Patient With Diabetic Ketoacidosis and Normokalemia

Early repolarization (ER) changes, characterized by J point elevation with or without ST-segment elevation, are dynamic in their presentation and can be exacerbated by factors such as hypothermia, hypercalcemia, vagotonia, and certain medications. There is limited research regarding the mechanism of...

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Autores principales: Khachatryan, Aleksan, Chow, Robert D, Harutyunyan, Hakob, Tamazyan, Vahagn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329200/
https://www.ncbi.nlm.nih.gov/pubmed/37426398
http://dx.doi.org/10.7759/cureus.41546
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author Khachatryan, Aleksan
Chow, Robert D
Harutyunyan, Hakob
Tamazyan, Vahagn
author_facet Khachatryan, Aleksan
Chow, Robert D
Harutyunyan, Hakob
Tamazyan, Vahagn
author_sort Khachatryan, Aleksan
collection PubMed
description Early repolarization (ER) changes, characterized by J point elevation with or without ST-segment elevation, are dynamic in their presentation and can be exacerbated by factors such as hypothermia, hypercalcemia, vagotonia, and certain medications. There is limited research regarding the mechanism of these changes and the dynamic changes of ER secondary to diabetic ketoacidosis (DKA). This case report highlights the augmentation of early repolarization changes resembling ST-segment elevation myocardial infarction (STEMI) in a patient with DKA that resolved with the treatment of acidosis. The misinterpretation of ER changes on electrocardiogram (ECG) as STEMI or pericarditis may result in the inappropriate utilization of resources, increased patient risk, and elevated morbidity and mortality. Recognition of the potential of DKA to cause ER changes can potentially avoid these unfavorable outcomes.
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spelling pubmed-103292002023-07-09 Early Repolarization Augmentation Mimicking Pseudo-Infarction in a Patient With Diabetic Ketoacidosis and Normokalemia Khachatryan, Aleksan Chow, Robert D Harutyunyan, Hakob Tamazyan, Vahagn Cureus Cardiology Early repolarization (ER) changes, characterized by J point elevation with or without ST-segment elevation, are dynamic in their presentation and can be exacerbated by factors such as hypothermia, hypercalcemia, vagotonia, and certain medications. There is limited research regarding the mechanism of these changes and the dynamic changes of ER secondary to diabetic ketoacidosis (DKA). This case report highlights the augmentation of early repolarization changes resembling ST-segment elevation myocardial infarction (STEMI) in a patient with DKA that resolved with the treatment of acidosis. The misinterpretation of ER changes on electrocardiogram (ECG) as STEMI or pericarditis may result in the inappropriate utilization of resources, increased patient risk, and elevated morbidity and mortality. Recognition of the potential of DKA to cause ER changes can potentially avoid these unfavorable outcomes. Cureus 2023-07-07 /pmc/articles/PMC10329200/ /pubmed/37426398 http://dx.doi.org/10.7759/cureus.41546 Text en Copyright © 2023, Khachatryan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Khachatryan, Aleksan
Chow, Robert D
Harutyunyan, Hakob
Tamazyan, Vahagn
Early Repolarization Augmentation Mimicking Pseudo-Infarction in a Patient With Diabetic Ketoacidosis and Normokalemia
title Early Repolarization Augmentation Mimicking Pseudo-Infarction in a Patient With Diabetic Ketoacidosis and Normokalemia
title_full Early Repolarization Augmentation Mimicking Pseudo-Infarction in a Patient With Diabetic Ketoacidosis and Normokalemia
title_fullStr Early Repolarization Augmentation Mimicking Pseudo-Infarction in a Patient With Diabetic Ketoacidosis and Normokalemia
title_full_unstemmed Early Repolarization Augmentation Mimicking Pseudo-Infarction in a Patient With Diabetic Ketoacidosis and Normokalemia
title_short Early Repolarization Augmentation Mimicking Pseudo-Infarction in a Patient With Diabetic Ketoacidosis and Normokalemia
title_sort early repolarization augmentation mimicking pseudo-infarction in a patient with diabetic ketoacidosis and normokalemia
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329200/
https://www.ncbi.nlm.nih.gov/pubmed/37426398
http://dx.doi.org/10.7759/cureus.41546
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