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The Effects of Graded Levels of Calorie Restriction: XIX. Impact of Graded Calorie Restriction on Protein Expression in the Liver

Calorie restriction (CR) extends life span by modulating the mechanisms involved in aging. We quantified the hepatic proteome of male C57BL/6 mice exposed to graded levels of CR (0%–40% CR) for 3 months, and evaluated which signaling pathways were most affected. The metabolic pathways most significa...

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Detalles Bibliográficos
Autores principales: Wang, Lu, Derous, Davina, Huang, Xiahe, Mitchell, Sharon E, Douglas, Alex, Lusseau, David, Wang, Yingchun, Speakman, John R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329235/
https://www.ncbi.nlm.nih.gov/pubmed/36757838
http://dx.doi.org/10.1093/gerona/glad017