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Losartan enhances the suppressive effect of pirfenidone on the bleomycin-induced epithelial-mesenchymal transition and oxidative stress in A549 cell line

OBJECTIVE(S): Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease. Despite the promising anti-fibrotic effect, the toleration of pirfenidone (PFD) by the patients in full dose is low. Combination therapy is a method for enhancing the therapeutic efficiency of PFD and decreasing its dose. The...

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Detalles Bibliográficos
Autores principales:	Amirkhosravi, Arian, Heidari, Mahmoud Reza, Karami-Mohajeri, Somayyeh, Torshabi, Maryam, Mandegary, Ali, Mehrabani, Mehrnaz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mashhad University of Medical Sciences 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329237/ https://www.ncbi.nlm.nih.gov/pubmed/37427320 http://dx.doi.org/10.22038/IJBMS.2023.68982.15035

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