CD8 + T-cell marker genes reveal different immune subtypes of oral lichen planus by integrating single-cell RNA-seq and bulk RNA-sequencing

BACKGROUND: Oral lichen planus (OLP) is a local autoimmune disease induced by T-cell dysfunction that frequently affects middle-aged or elderly people, with a higher prevalence in women. CD8 + T cells, also known as killer T cells, play an important role in the progression and persistence of OLP. In...

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Detalles Bibliográficos
Autores principales: Zhang, Jinhao, Peng, Gaoge, Chi, Hao, Yang, Jinyan, Xie, Xixi, Song, Guobin, Tran, Lisa Jia, Xia, Zhijia, Tian, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329325/
https://www.ncbi.nlm.nih.gov/pubmed/37422617
http://dx.doi.org/10.1186/s12903-023-03138-0

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