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AnnoDash, a clinical terminology annotation dashboard
BACKGROUND: Standard ontologies are critical for interoperability and multisite analyses of health data. Nevertheless, mapping concepts to ontologies is often done with generic tools and is labor-intensive. Contextualizing candidate concepts within source data is also done in an ad hoc manner. METHO...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329488/ https://www.ncbi.nlm.nih.gov/pubmed/37425489 http://dx.doi.org/10.1093/jamiaopen/ooad046 |
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author | Xu, Justin Mazwi, Mjaye Johnson, Alistair E W |
author_facet | Xu, Justin Mazwi, Mjaye Johnson, Alistair E W |
author_sort | Xu, Justin |
collection | PubMed |
description | BACKGROUND: Standard ontologies are critical for interoperability and multisite analyses of health data. Nevertheless, mapping concepts to ontologies is often done with generic tools and is labor-intensive. Contextualizing candidate concepts within source data is also done in an ad hoc manner. METHODS AND RESULTS: We present AnnoDash, a flexible dashboard to support annotation of concepts with terms from a given ontology. Text-based similarity is used to identify likely matches, and large language models are used to improve ontology ranking. A convenient interface is provided to visualize observations associated with a concept, supporting the disambiguation of vague concept descriptions. Time-series plots contrast the concept with known clinical measurements. We evaluated the dashboard qualitatively against several ontologies (SNOMED CT, LOINC, etc.) by using MIMIC-IV measurements. The dashboard is web-based and step-by-step instructions for deployment are provided, simplifying usage for nontechnical audiences. The modular code structure enables users to extend upon components, including improving similarity scoring, constructing new plots, or configuring new ontologies. CONCLUSION: AnnoDash, an improved clinical terminology annotation tool, can facilitate data harmonizing by promoting mapping of clinical data. AnnoDash is freely available at https://github.com/justin13601/AnnoDash (https://doi.org/10.5281/zenodo.8043943). |
format | Online Article Text |
id | pubmed-10329488 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-103294882023-07-09 AnnoDash, a clinical terminology annotation dashboard Xu, Justin Mazwi, Mjaye Johnson, Alistair E W JAMIA Open Application Notes BACKGROUND: Standard ontologies are critical for interoperability and multisite analyses of health data. Nevertheless, mapping concepts to ontologies is often done with generic tools and is labor-intensive. Contextualizing candidate concepts within source data is also done in an ad hoc manner. METHODS AND RESULTS: We present AnnoDash, a flexible dashboard to support annotation of concepts with terms from a given ontology. Text-based similarity is used to identify likely matches, and large language models are used to improve ontology ranking. A convenient interface is provided to visualize observations associated with a concept, supporting the disambiguation of vague concept descriptions. Time-series plots contrast the concept with known clinical measurements. We evaluated the dashboard qualitatively against several ontologies (SNOMED CT, LOINC, etc.) by using MIMIC-IV measurements. The dashboard is web-based and step-by-step instructions for deployment are provided, simplifying usage for nontechnical audiences. The modular code structure enables users to extend upon components, including improving similarity scoring, constructing new plots, or configuring new ontologies. CONCLUSION: AnnoDash, an improved clinical terminology annotation tool, can facilitate data harmonizing by promoting mapping of clinical data. AnnoDash is freely available at https://github.com/justin13601/AnnoDash (https://doi.org/10.5281/zenodo.8043943). Oxford University Press 2023-07-08 /pmc/articles/PMC10329488/ /pubmed/37425489 http://dx.doi.org/10.1093/jamiaopen/ooad046 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of the American Medical Informatics Association. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Application Notes Xu, Justin Mazwi, Mjaye Johnson, Alistair E W AnnoDash, a clinical terminology annotation dashboard |
title | AnnoDash, a clinical terminology annotation dashboard |
title_full | AnnoDash, a clinical terminology annotation dashboard |
title_fullStr | AnnoDash, a clinical terminology annotation dashboard |
title_full_unstemmed | AnnoDash, a clinical terminology annotation dashboard |
title_short | AnnoDash, a clinical terminology annotation dashboard |
title_sort | annodash, a clinical terminology annotation dashboard |
topic | Application Notes |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329488/ https://www.ncbi.nlm.nih.gov/pubmed/37425489 http://dx.doi.org/10.1093/jamiaopen/ooad046 |
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