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MDTips: a multimodal-data-based drug–target interaction prediction system fusing knowledge, gene expression profile, and structural data

MOTIVATION: Screening new drug–target interactions (DTIs) by traditional experimental methods is costly and time-consuming. Recent advances in knowledge graphs, chemical linear notations, and genomic data enable researchers to develop computational-based-DTI models, which play a pivotal role in drug...

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Detalles Bibliográficos
Autores principales: Xia, Xiaoqiong, Zhu, Chaoyu, Zhong, Fan, Liu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329491/
https://www.ncbi.nlm.nih.gov/pubmed/37379157
http://dx.doi.org/10.1093/bioinformatics/btad411