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Congenital toxoplasmosis among hospitalized infants in Poland in the years 2007–2021: study based on the national hospital registry

Congenital toxoplasmosis (CT) is a rare entity and it may pose a life-threatening risk for the newborns. The aim of the study was to evaluate the incidence and other selected factors of CT in Poland. Our study is a population-based study on CT patients in 2007–2021. The study was based on 1504 hospi...

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Autores principales: Rząd, Michał, Kanecki, Krzysztof, Lewtak, Katarzyna, Goryński, Paweł, Tyszko, Piotr, Lewandowska-Andruszuk, Izabela, Nitsch-Osuch, Aneta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329637/
https://www.ncbi.nlm.nih.gov/pubmed/37422492
http://dx.doi.org/10.1038/s41598-023-38270-y
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author Rząd, Michał
Kanecki, Krzysztof
Lewtak, Katarzyna
Goryński, Paweł
Tyszko, Piotr
Lewandowska-Andruszuk, Izabela
Nitsch-Osuch, Aneta
author_facet Rząd, Michał
Kanecki, Krzysztof
Lewtak, Katarzyna
Goryński, Paweł
Tyszko, Piotr
Lewandowska-Andruszuk, Izabela
Nitsch-Osuch, Aneta
author_sort Rząd, Michał
collection PubMed
description Congenital toxoplasmosis (CT) is a rare entity and it may pose a life-threatening risk for the newborns. The aim of the study was to evaluate the incidence and other selected factors of CT in Poland. Our study is a population-based study on CT patients in 2007–2021. The study was based on 1504 hospitalization records of first-time diagnosis of CT in newborns. In the study group, we observed 763 males (50.7%) and 741 females (49.3%). The mean and median age was 31 days and 10 days, respectively. Based on the hospital registry, the mean annual CT incidence was estimated to be 2.6 per 10,000 live births (95% CI 2.0–3.2 per 10,000 live births). The incidence of CT cases fluctuated over the years 2007–2021, with the highest incidence in 2010 and the lowest one in 2014. There were no statistically significant differences between the incidence of CT in relation to sex or place of residence. The periodic fluctuations in the number of cases of congenital toxoplasmosis indicates the need to develop effective prevention programs to effectively counteract the disease and its consequences.
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spelling pubmed-103296372023-07-10 Congenital toxoplasmosis among hospitalized infants in Poland in the years 2007–2021: study based on the national hospital registry Rząd, Michał Kanecki, Krzysztof Lewtak, Katarzyna Goryński, Paweł Tyszko, Piotr Lewandowska-Andruszuk, Izabela Nitsch-Osuch, Aneta Sci Rep Article Congenital toxoplasmosis (CT) is a rare entity and it may pose a life-threatening risk for the newborns. The aim of the study was to evaluate the incidence and other selected factors of CT in Poland. Our study is a population-based study on CT patients in 2007–2021. The study was based on 1504 hospitalization records of first-time diagnosis of CT in newborns. In the study group, we observed 763 males (50.7%) and 741 females (49.3%). The mean and median age was 31 days and 10 days, respectively. Based on the hospital registry, the mean annual CT incidence was estimated to be 2.6 per 10,000 live births (95% CI 2.0–3.2 per 10,000 live births). The incidence of CT cases fluctuated over the years 2007–2021, with the highest incidence in 2010 and the lowest one in 2014. There were no statistically significant differences between the incidence of CT in relation to sex or place of residence. The periodic fluctuations in the number of cases of congenital toxoplasmosis indicates the need to develop effective prevention programs to effectively counteract the disease and its consequences. Nature Publishing Group UK 2023-07-08 /pmc/articles/PMC10329637/ /pubmed/37422492 http://dx.doi.org/10.1038/s41598-023-38270-y Text en © The Author(s) 2023, corrected publication 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Rząd, Michał
Kanecki, Krzysztof
Lewtak, Katarzyna
Goryński, Paweł
Tyszko, Piotr
Lewandowska-Andruszuk, Izabela
Nitsch-Osuch, Aneta
Congenital toxoplasmosis among hospitalized infants in Poland in the years 2007–2021: study based on the national hospital registry
title Congenital toxoplasmosis among hospitalized infants in Poland in the years 2007–2021: study based on the national hospital registry
title_full Congenital toxoplasmosis among hospitalized infants in Poland in the years 2007–2021: study based on the national hospital registry
title_fullStr Congenital toxoplasmosis among hospitalized infants in Poland in the years 2007–2021: study based on the national hospital registry
title_full_unstemmed Congenital toxoplasmosis among hospitalized infants in Poland in the years 2007–2021: study based on the national hospital registry
title_short Congenital toxoplasmosis among hospitalized infants in Poland in the years 2007–2021: study based on the national hospital registry
title_sort congenital toxoplasmosis among hospitalized infants in poland in the years 2007–2021: study based on the national hospital registry
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329637/
https://www.ncbi.nlm.nih.gov/pubmed/37422492
http://dx.doi.org/10.1038/s41598-023-38270-y
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