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Physiologically relevant acid-sensing ion channel (ASIC) 2a/3 heteromers have a 1:2 stoichiometry

Acid-sensing ion channels (ASICs) sense extracellular protons and are involved in synaptic transmission and pain sensation. ASIC1a and ASIC3 are the ASIC subunits with the highest proton sensitivity. ASIC2a in contrast has low proton sensitivity but increases the variability of ASICs by forming hete...

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Detalles Bibliográficos
Autores principales:	Fischer, Leon, Schmidt, Axel, Dopychai, Anke, Joussen, Sylvia, Joeres, Niko, Oslender-Bujotzek, Adrienne, Schmalzing, Günther, Gründer, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329638/ https://www.ncbi.nlm.nih.gov/pubmed/37422581 http://dx.doi.org/10.1038/s42003-023-05087-4

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