DNA 5-methylcytosine detection and methylation phasing using PacBio circular consensus sequencing

Long single-molecular sequencing technologies, such as PacBio circular consensus sequencing (CCS) and nanopore sequencing, are advantageous in detecting DNA 5-methylcytosine in CpGs (5mCpGs), especially in repetitive genomic regions. However, existing methods for detecting 5mCpGs using PacBio CCS ar...

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Detalles Bibliográficos
Autores principales: Ni, Peng, Nie, Fan, Zhong, Zeyu, Xu, Jinrui, Huang, Neng, Zhang, Jun, Zhao, Haochen, Zou, You, Huang, Yuanfeng, Li, Jinchen, Xiao, Chuan-Le, Luo, Feng, Wang, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329642/
https://www.ncbi.nlm.nih.gov/pubmed/37422489
http://dx.doi.org/10.1038/s41467-023-39784-9

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