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The ELK3-DRP1 axis determines the chemosensitivity of triple-negative breast cancer cells to CDDP by regulating mitochondrial dynamics

Triple-negative breast cancer (TNBC) is the most lethal form of breast cancer. TNBC patients have higher rates of metastasis and restricted therapy options. Although chemotherapy is the conventional treatment for TNBC, the frequent occurrence of chemoresistance significantly lowers the efficacy of t...

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Detalles Bibliográficos
Autores principales: Park, Joo Dong, Jang, Hye Jung, Choi, Seung Hee, Jo, Gae Hoon, Choi, Jin-Ho, Hwang, Sohyun, Park, Wooram, Park, Kyung-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329652/
https://www.ncbi.nlm.nih.gov/pubmed/37422450
http://dx.doi.org/10.1038/s41420-023-01536-5