The structural pathology for hypophosphatasia caused by malfunctional tissue non-specific alkaline phosphatase

Hypophosphatasia (HPP) is a metabolic bone disease that manifests as developmental abnormalities in bone and dental tissues. HPP patients exhibit hypo-mineralization and osteopenia due to the deficiency or malfunction of tissue non-specific alkaline phosphatase (TNAP), which catalyzes the hydrolysis...

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Detalles Bibliográficos
Autores principales: Yu, Yating, Rong, Kewei, Yao, Deqiang, Zhang, Qing, Cao, Xiankun, Rao, Bing, Xia, Ying, Lu, Yi, Shen, Yafeng, Yao, Ying, Xu, Hongtao, Ma, Peixiang, Cao, Yu, Qin, An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329691/
https://www.ncbi.nlm.nih.gov/pubmed/37422472
http://dx.doi.org/10.1038/s41467-023-39833-3

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