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Regulatory architecture of housekeeping genes is driven by promoter assemblies
Genes that are key to cell identity are generally regulated by cell-type-specific enhancer elements bound by transcription factors, some of which facilitate looping to distant gene promoters. In contrast, genes that encode housekeeping functions, whose regulation is essential for normal cell metabol...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329844/ https://www.ncbi.nlm.nih.gov/pubmed/37182209 http://dx.doi.org/10.1016/j.celrep.2023.112505 |