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Risk Factors Associated With Intrauterine Growth Restriction: A Case-Control Study

Background Intrauterine growth restriction (IUGR) is a disorder in which the fetus fails to reach its genetic development potential and is considered to be present when the weight at birth is less than the 10th percentile; as a result, it is at risk of increased postnatal morbidity and mortality. Ev...

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Autores principales: Dapkekar, Priyanka, Bhalerao, Anuja, Kawathalkar, Anjali, Vijay, Nikita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329857/
https://www.ncbi.nlm.nih.gov/pubmed/37431363
http://dx.doi.org/10.7759/cureus.40178
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author Dapkekar, Priyanka
Bhalerao, Anuja
Kawathalkar, Anjali
Vijay, Nikita
author_facet Dapkekar, Priyanka
Bhalerao, Anuja
Kawathalkar, Anjali
Vijay, Nikita
author_sort Dapkekar, Priyanka
collection PubMed
description Background Intrauterine growth restriction (IUGR) is a disorder in which the fetus fails to reach its genetic development potential and is considered to be present when the weight at birth is less than the 10th percentile; as a result, it is at risk of increased postnatal morbidity and mortality. Every year, approximately 24% of newborns worldwide are determined to have IUGR. The objective of the present study was to identify various sociodemographic, medical, and obstetric risk factors associated with IUGR. Methodology A case-control study was conducted from January 2020 to December 2022. Fifty-four cases and 54 controls were included in the study. Postnatal women with neonates having birth weight below the 10th percentile for gestational age (GA) were recruited as cases in the study. Control cases were postnatal women with neonatal birth weight appropriate for (GA). Detailed history with respect to socio-demographic, medical, and obstetric parameters was noted and compared. Results Among the sociodemographic factors, only socioeconomic status showed significant statistical differences with the age group of 21 to 25 years showing maximum (51.9%) IUGR cases. Among the maternal risk factors, anemia (29.6%) and hypertensive disorders of pregnancy (22.2%) were marked as significant risk factors for IUGR. There was no significant difference in the distribution of past medical and obstetric histories between the two research groups. Conclusion Due to the poor living conditions, low literacy rates, and general lack of knowledge, low socioeconomic level increases the risk of IUGR. This leads to nutritional deficiencies and insufficient growth environment which results in anemia and hypertensive disorders of pregnancy which are potent risk factors for IUGR. IUGR may be caused by maternal risk factors as well as past medical and obstetric conditions. However, for the risk factor of IUGR, the birth weight at the time of delivery could be taken into consideration as well.
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spelling pubmed-103298572023-07-10 Risk Factors Associated With Intrauterine Growth Restriction: A Case-Control Study Dapkekar, Priyanka Bhalerao, Anuja Kawathalkar, Anjali Vijay, Nikita Cureus Obstetrics/Gynecology Background Intrauterine growth restriction (IUGR) is a disorder in which the fetus fails to reach its genetic development potential and is considered to be present when the weight at birth is less than the 10th percentile; as a result, it is at risk of increased postnatal morbidity and mortality. Every year, approximately 24% of newborns worldwide are determined to have IUGR. The objective of the present study was to identify various sociodemographic, medical, and obstetric risk factors associated with IUGR. Methodology A case-control study was conducted from January 2020 to December 2022. Fifty-four cases and 54 controls were included in the study. Postnatal women with neonates having birth weight below the 10th percentile for gestational age (GA) were recruited as cases in the study. Control cases were postnatal women with neonatal birth weight appropriate for (GA). Detailed history with respect to socio-demographic, medical, and obstetric parameters was noted and compared. Results Among the sociodemographic factors, only socioeconomic status showed significant statistical differences with the age group of 21 to 25 years showing maximum (51.9%) IUGR cases. Among the maternal risk factors, anemia (29.6%) and hypertensive disorders of pregnancy (22.2%) were marked as significant risk factors for IUGR. There was no significant difference in the distribution of past medical and obstetric histories between the two research groups. Conclusion Due to the poor living conditions, low literacy rates, and general lack of knowledge, low socioeconomic level increases the risk of IUGR. This leads to nutritional deficiencies and insufficient growth environment which results in anemia and hypertensive disorders of pregnancy which are potent risk factors for IUGR. IUGR may be caused by maternal risk factors as well as past medical and obstetric conditions. However, for the risk factor of IUGR, the birth weight at the time of delivery could be taken into consideration as well. Cureus 2023-06-09 /pmc/articles/PMC10329857/ /pubmed/37431363 http://dx.doi.org/10.7759/cureus.40178 Text en Copyright © 2023, Dapkekar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Obstetrics/Gynecology
Dapkekar, Priyanka
Bhalerao, Anuja
Kawathalkar, Anjali
Vijay, Nikita
Risk Factors Associated With Intrauterine Growth Restriction: A Case-Control Study
title Risk Factors Associated With Intrauterine Growth Restriction: A Case-Control Study
title_full Risk Factors Associated With Intrauterine Growth Restriction: A Case-Control Study
title_fullStr Risk Factors Associated With Intrauterine Growth Restriction: A Case-Control Study
title_full_unstemmed Risk Factors Associated With Intrauterine Growth Restriction: A Case-Control Study
title_short Risk Factors Associated With Intrauterine Growth Restriction: A Case-Control Study
title_sort risk factors associated with intrauterine growth restriction: a case-control study
topic Obstetrics/Gynecology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329857/
https://www.ncbi.nlm.nih.gov/pubmed/37431363
http://dx.doi.org/10.7759/cureus.40178
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