Prolonged voluntary wheel running reveals unique adaptations in mdx mice treated with microdystrophin constructs ± the nNOS-binding site

We tested the effects of prolonged voluntary wheel running on the muscle function of mdx mice treated with one of two different microdystrophin constructs. At 7 weeks of age mdx mice were injected with a single dose of AAV9-CK8-microdystrophin with (gene therapy 1, GT1) or without (gene therapy 2, G...

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Detalles Bibliográficos
Autores principales: Hamm, S. E., Yuan, C., McQueen, L. F., Wallace, M. A., Zhang, H., Arora, A., Garafalo, A. M., McMillan, R. P., Lawlor, M. W., Prom, M. J., Ott, E. M., Yan, J., Addington, A. K., Morris, C. A., Gonzalez, J. P., Grange, R. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10330712/
https://www.ncbi.nlm.nih.gov/pubmed/37435312
http://dx.doi.org/10.3389/fphys.2023.1166206

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