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Extracellular matrix-derived peptide stimulates the generation of endocrine progenitors and islet organoids from iPSCs
Induced pluripotent stem cells (iPSCs) have enormous potential in producing human tissues endlessly. We previously reported that type V collagen (COL5), a pancreatic extracellular matrix protein, promotes islet development and maturation from iPSCs. In this study, we identified a bioactive peptide d...
Autores principales: | Heaton, Emma S, Hu, Ming, Liu, Tianzheng, Hui, Huang, Tan, Yinfei, Ye, Kaiming, Jin, Sha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331343/ https://www.ncbi.nlm.nih.gov/pubmed/37435573 http://dx.doi.org/10.1177/20417314231185858 |
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