ASXL3 gene mutations inhibit cell proliferation and promote cell apoptosis in mouse cardiomyocytes by upregulating lncRNA NONMMUT063967.2

Congenital heart disease (CHD) is a serious condition with unknown etiology. In a recent study, a compound heterozygous mutation (c.3526C > T [p.Arg1176Trp] and c.4643A > G [p.Asp1548Gly]) in the ASXL3 gene was identified, which is associated with CHD. This mutation was overexpressed in HL-1 m...

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Detalles Bibliográficos
Autores principales: Liu, Zequn, Jiang, Yanmin, Fang, Fu, Li, Ru, Han, Jin, Yang, Xin, Deng, Qiong, Li, Lu-Shan, Lei, Ting-ying, Li, Dong-Zhi, Liao, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331400/
https://www.ncbi.nlm.nih.gov/pubmed/37435360
http://dx.doi.org/10.1016/j.bbrep.2023.101505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331400/
https://www.ncbi.nlm.nih.gov/pubmed/37435360
http://dx.doi.org/10.1016/j.bbrep.2023.101505

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