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Identification of signaling pathways modifying human dopaminergic neuron development using a pluripotent stem cell-based high-throughput screening automated system: purinergic pathways as a proof-of-principle
Introduction: Alteration in the development, maturation, and projection of dopaminergic neurons has been proposed to be associated with several neurological and psychiatric disorders. Therefore, understanding the signals modulating the genesis of human dopaminergic neurons is crucial to elucidate di...
Autores principales: | Boissart, Claire, Lasbareilles, Marie, Tournois, Johana, Chatrousse, Laure, Poullion, Thifaine, Benchoua, Alexandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331426/ https://www.ncbi.nlm.nih.gov/pubmed/37435497 http://dx.doi.org/10.3389/fphar.2023.1152180 |
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