IFITM1 inhibits trophoblast invasion and is induced in placentas associated with IFN-mediated pregnancy diseases

Interferon-induced transmembrane proteins (IFITMs) are restriction factors that block many viruses from entering cells. High levels of type I interferon (IFN) are associated with adverse pregnancy outcomes, and IFITMs have been shown to impair the formation of syncytiotrophoblast. Here, we examine w...

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Detalles Bibliográficos
Autores principales: Degrelle, Séverine A., Buchrieser, Julian, Dupressoir, Anne, Porrot, Françoise, Loeuillet, Laurence, Schwartz, Olivier, Fournier, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331461/
https://www.ncbi.nlm.nih.gov/pubmed/37434700
http://dx.doi.org/10.1016/j.isci.2023.107147

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