Efficient chimeric antigen receptor targeting of a central epitope of CD22

Chimeric antigen receptor (CAR) T-cell therapy has had considerable success in the treatment of B-cell malignancies. Targeting the B-lineage marker CD19 has brought great advances to the treatment of acute lymphoblastic leukemia and B-cell lymphomas. However, relapse remains an issue in many cases....

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Detalles Bibliográficos
Autores principales: Casey, Nicholas Paul, Klee, Clara Helena, Fåne, Anne, Caulier, Benjamin, Graczyk-Jarzynka, Agnieszka, Krawczyk, Marta, Fidyt, Klaudyna, Josefsson, Sarah E., Köksal, Hakan, Dillard, Pierre, Patkowska, Elzbieta, Firczuk, Malgorzata, Smeland, Erlend B., Winiarska, Magdalena, Myklebust, June H., Inderberg, Else Marit, Wälchli, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331463/
https://www.ncbi.nlm.nih.gov/pubmed/37269947
http://dx.doi.org/10.1016/j.jbc.2023.104883

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