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Measuring cell deformation by microfluidics
Microfluidics is an increasingly popular method for studying cell deformation, with various applications in fields such as cell biology, biophysics, and medical research. Characterizing cell deformation offers insights into fundamental cell processes, such as migration, division, and signaling. This...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331473/ https://www.ncbi.nlm.nih.gov/pubmed/37434754 http://dx.doi.org/10.3389/fbioe.2023.1214544 |
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author | An, Ling Ji, Fenglong Zhao, Enming Liu, Yi Liu, Yaling |
author_facet | An, Ling Ji, Fenglong Zhao, Enming Liu, Yi Liu, Yaling |
author_sort | An, Ling |
collection | PubMed |
description | Microfluidics is an increasingly popular method for studying cell deformation, with various applications in fields such as cell biology, biophysics, and medical research. Characterizing cell deformation offers insights into fundamental cell processes, such as migration, division, and signaling. This review summarizes recent advances in microfluidic techniques for measuring cellular deformation, including the different types of microfluidic devices and methods used to induce cell deformation. Recent applications of microfluidics-based approaches for studying cell deformation are highlighted. Compared to traditional methods, microfluidic chips can control the direction and velocity of cell flow by establishing microfluidic channels and microcolumn arrays, enabling the measurement of cell shape changes. Overall, microfluidics-based approaches provide a powerful platform for studying cell deformation. It is expected that future developments will lead to more intelligent and diverse microfluidic chips, further promoting the application of microfluidics-based methods in biomedical research, providing more effective tools for disease diagnosis, drug screening, and treatment. |
format | Online Article Text |
id | pubmed-10331473 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-103314732023-07-11 Measuring cell deformation by microfluidics An, Ling Ji, Fenglong Zhao, Enming Liu, Yi Liu, Yaling Front Bioeng Biotechnol Bioengineering and Biotechnology Microfluidics is an increasingly popular method for studying cell deformation, with various applications in fields such as cell biology, biophysics, and medical research. Characterizing cell deformation offers insights into fundamental cell processes, such as migration, division, and signaling. This review summarizes recent advances in microfluidic techniques for measuring cellular deformation, including the different types of microfluidic devices and methods used to induce cell deformation. Recent applications of microfluidics-based approaches for studying cell deformation are highlighted. Compared to traditional methods, microfluidic chips can control the direction and velocity of cell flow by establishing microfluidic channels and microcolumn arrays, enabling the measurement of cell shape changes. Overall, microfluidics-based approaches provide a powerful platform for studying cell deformation. It is expected that future developments will lead to more intelligent and diverse microfluidic chips, further promoting the application of microfluidics-based methods in biomedical research, providing more effective tools for disease diagnosis, drug screening, and treatment. Frontiers Media S.A. 2023-06-27 /pmc/articles/PMC10331473/ /pubmed/37434754 http://dx.doi.org/10.3389/fbioe.2023.1214544 Text en Copyright © 2023 An, Ji, Zhao, Liu and Liu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Bioengineering and Biotechnology An, Ling Ji, Fenglong Zhao, Enming Liu, Yi Liu, Yaling Measuring cell deformation by microfluidics |
title | Measuring cell deformation by microfluidics |
title_full | Measuring cell deformation by microfluidics |
title_fullStr | Measuring cell deformation by microfluidics |
title_full_unstemmed | Measuring cell deformation by microfluidics |
title_short | Measuring cell deformation by microfluidics |
title_sort | measuring cell deformation by microfluidics |
topic | Bioengineering and Biotechnology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331473/ https://www.ncbi.nlm.nih.gov/pubmed/37434754 http://dx.doi.org/10.3389/fbioe.2023.1214544 |
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