PCSK9 inhibition interrupts the cross-talk between keratinocytes and macrophages and prevents UVB-induced skin damage

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an enzyme that promotes the degradation of low-density lipoprotein receptors. It is involved in hyperlipidemia as well as other diseases, such as cancer and skin inflammation. However, the detailed mechanism for PCSK9 on ultraviolet B (UVB)-in...

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Detalles Bibliográficos
Autores principales: Luan, Chao, He, Yingxue, Liu, Wen, Rong, Yicheng, Gao, Jian, Xu, Kang, Yu, Hui, Hu, Yu, Zhang, Jiaan, Chen, Kun, Guo, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331474/
https://www.ncbi.nlm.nih.gov/pubmed/37290532
http://dx.doi.org/10.1016/j.jbc.2023.104895

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