The acyltransferase Gpc1 is both a target and an effector of the unfolded protein response in Saccharomyces cerevisiae

The unfolded protein response (UPR) is sensitive to proteotoxic and membrane bilayer stress, both of which are sensed by the ER protein Ire1. When activated, Ire1 splices HAC1 mRNA, producing a transcription factor that targets genes involved in proteostasis and lipid metabolism, among others. The m...

Descripción completa

Detalles Bibliográficos
Autores principales: Hrach, Victoria Lee, King, William R., Nelson, Laura D., Conklin, Shane, Pollock, John A., Patton-Vogt, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331479/
https://www.ncbi.nlm.nih.gov/pubmed/37269946
http://dx.doi.org/10.1016/j.jbc.2023.104884

Ejemplares similares

Ejemplares similares