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Click chemistry-based thiol redox proteomics reveals significant cysteine reduction induced by chronic ethanol consumption

In the U.S., alcohol-associated liver disease (ALD) impacts millions of people and is a major healthcare burden. While the pathology of ALD is unmistakable, the molecular mechanisms underlying ethanol hepatotoxicity are not fully understood. Hepatic ethanol metabolism is intimately linked with alter...

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Detalles Bibliográficos
Autores principales: Harris, Peter S., McGinnis, Courtney D., Michel, Cole R., Marentette, John O., Reisdorph, Richard, Roede, James R., Fritz, Kristofer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331594/
https://www.ncbi.nlm.nih.gov/pubmed/37390786
http://dx.doi.org/10.1016/j.redox.2023.102792