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Childhood adversity and late-life depression: moderated mediation model of stress and social support
BACKGROUND: As life expectancy increases, understanding the mechanism for late-life depression and finding a crucial moderator becomes more important for mental health in older adults. Childhood adversity increases the risk of clinical depression even in old age. Based on the stress sensitivity theo...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331618/ https://www.ncbi.nlm.nih.gov/pubmed/37435403 http://dx.doi.org/10.3389/fpsyt.2023.1183884 |
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author | Lee, Jin-kyung Lee, Jinhee Chung, Moo-Kwon Park, Ji Young Shin, Taeksoo Lee, Kyoung-Joung Lim, Hyo-Sang Hwang, Sangwon Urtnasan, Erdenebayar Jo, Yongmie Kim, Min-Hyuk |
author_facet | Lee, Jin-kyung Lee, Jinhee Chung, Moo-Kwon Park, Ji Young Shin, Taeksoo Lee, Kyoung-Joung Lim, Hyo-Sang Hwang, Sangwon Urtnasan, Erdenebayar Jo, Yongmie Kim, Min-Hyuk |
author_sort | Lee, Jin-kyung |
collection | PubMed |
description | BACKGROUND: As life expectancy increases, understanding the mechanism for late-life depression and finding a crucial moderator becomes more important for mental health in older adults. Childhood adversity increases the risk of clinical depression even in old age. Based on the stress sensitivity theory and stress-buffering effects, stress would be a significant mediator, while social support can be a key moderator in the mediation pathways. However, few studies have tested this moderated mediation model with a sample of older adults. This study aims to reveal the association between childhood adversity and late-life depression in older adults, taking into consideration the effects of stress and social support. METHODS: This study used several path models to analyze the data from 622 elderly participants who were never diagnosed with clinical depression. RESULTS: We found that childhood adversity increases the odds ratio of depression by approximately 20% in older adults. Path model with mediation demonstrates that stress fully mediates the pathway from childhood adversity to late-life depression. Path model with moderated mediation also illustrates that social support significantly weakens the association between childhood adversity and perceived stress. CONCLUSION: This study provides empirical evidence to reveal a more detailed mechanism for late-life depression. Specifically, this study identifies one crucial risk factor and one protective factor, stress and social support, respectively. This brings insight into prevention of late-life depression among those who have experienced childhood adversity. |
format | Online Article Text |
id | pubmed-10331618 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-103316182023-07-11 Childhood adversity and late-life depression: moderated mediation model of stress and social support Lee, Jin-kyung Lee, Jinhee Chung, Moo-Kwon Park, Ji Young Shin, Taeksoo Lee, Kyoung-Joung Lim, Hyo-Sang Hwang, Sangwon Urtnasan, Erdenebayar Jo, Yongmie Kim, Min-Hyuk Front Psychiatry Psychiatry BACKGROUND: As life expectancy increases, understanding the mechanism for late-life depression and finding a crucial moderator becomes more important for mental health in older adults. Childhood adversity increases the risk of clinical depression even in old age. Based on the stress sensitivity theory and stress-buffering effects, stress would be a significant mediator, while social support can be a key moderator in the mediation pathways. However, few studies have tested this moderated mediation model with a sample of older adults. This study aims to reveal the association between childhood adversity and late-life depression in older adults, taking into consideration the effects of stress and social support. METHODS: This study used several path models to analyze the data from 622 elderly participants who were never diagnosed with clinical depression. RESULTS: We found that childhood adversity increases the odds ratio of depression by approximately 20% in older adults. Path model with mediation demonstrates that stress fully mediates the pathway from childhood adversity to late-life depression. Path model with moderated mediation also illustrates that social support significantly weakens the association between childhood adversity and perceived stress. CONCLUSION: This study provides empirical evidence to reveal a more detailed mechanism for late-life depression. Specifically, this study identifies one crucial risk factor and one protective factor, stress and social support, respectively. This brings insight into prevention of late-life depression among those who have experienced childhood adversity. Frontiers Media S.A. 2023-06-26 /pmc/articles/PMC10331618/ /pubmed/37435403 http://dx.doi.org/10.3389/fpsyt.2023.1183884 Text en Copyright © 2023 Lee, Lee, Chung, Park, Shin, Lee, Lim, Hwang, Urtnasan, Jo and Kim. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Psychiatry Lee, Jin-kyung Lee, Jinhee Chung, Moo-Kwon Park, Ji Young Shin, Taeksoo Lee, Kyoung-Joung Lim, Hyo-Sang Hwang, Sangwon Urtnasan, Erdenebayar Jo, Yongmie Kim, Min-Hyuk Childhood adversity and late-life depression: moderated mediation model of stress and social support |
title | Childhood adversity and late-life depression: moderated mediation model of stress and social support |
title_full | Childhood adversity and late-life depression: moderated mediation model of stress and social support |
title_fullStr | Childhood adversity and late-life depression: moderated mediation model of stress and social support |
title_full_unstemmed | Childhood adversity and late-life depression: moderated mediation model of stress and social support |
title_short | Childhood adversity and late-life depression: moderated mediation model of stress and social support |
title_sort | childhood adversity and late-life depression: moderated mediation model of stress and social support |
topic | Psychiatry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331618/ https://www.ncbi.nlm.nih.gov/pubmed/37435403 http://dx.doi.org/10.3389/fpsyt.2023.1183884 |
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