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Bioactivity of recombinant humanized monoclonal antibody against HER2 in-vivo and in-vitro and its mechanism of action in ovarian cancer

BACKGROUND: Human epidermal growth factor receptor 2 (HER2) protein is overexpressed on the surface of various epithelial ovarian cancer tissues, mediates the proliferation, differentiation, metastasis, and signal transduction of tumor cells, and thus is a potential cancer therapeutic target. Howeve...

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Detalles Bibliográficos
Autores principales: Zeng, Jinfeng, Zhang, Hui, Guan, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331701/
https://www.ncbi.nlm.nih.gov/pubmed/37434690
http://dx.doi.org/10.21037/tcr-23-432

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