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Revisiting the pro-oxidant activity of copper: interplay of ascorbate, cysteine, and glutathione

Copper (Cu) is essential for most organisms, but it can be poisonous in excess, through mechanisms such as protein aggregation, trans-metallation, and oxidative stress. The latter could implicate the formation of potentially harmful reactive oxygen species (O(2)(•)(−), H(2)O(2), and HO(•)) via the r...

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Detalles Bibliográficos
Autores principales: Falcone, Enrico, Stellato, Francesco, Vileno, Bertrand, Bouraguba, Merwan, Lebrun, Vincent, Ilbert, Marianne, Morante, Silvia, Faller, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331802/
https://www.ncbi.nlm.nih.gov/pubmed/37353903
http://dx.doi.org/10.1093/mtomcs/mfad040