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Characterization of Natural Compounds as Inhibitors of NS1 Endonuclease from Canine Parvovirus Type 2

Canine parvovirus type 2 (CPV-2) has high morbidity and mortality rates in canines. Nonstructural protein 1 (NS1) of CPV-2 has endonuclease activity, initiates viral DNA replication, and is highly conserved. Thus, it is a promising target for antiviral inhibitor development. We overexpressed a 41.9...

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Detalles Bibliográficos
Autores principales:	Kwak, So-Hyung, Kim, Hayeong, Yun, Hyeli, Lim, Juho, Kang, Dong-Hyun, Kim, Doman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society for Microbiology and Biotechnology 2023
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331946/ https://www.ncbi.nlm.nih.gov/pubmed/36994623 http://dx.doi.org/10.4014/jmb.2211.11040

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