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The 29-nucleotide deletion in SARS-CoV: truncated versions of ORF8 are under purifying selection

BACKGROUND: Accessory proteins have diverse roles in coronavirus pathobiology. One of them in SARS-CoV (the causative agent of the severe acute respiratory syndrome outbreak in 2002–2003) is encoded by the open reading frame 8 (ORF8). Among the most dramatic genomic changes observed in SARS-CoV isol...

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Detalles Bibliográficos
Autores principales: Bykova, Anastassia, Saura, Andreu, Glazko, Galina V., Roche-Lima, Abiel, Yurchenko, Vyacheslav, Rogozin, Igor B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332002/
https://www.ncbi.nlm.nih.gov/pubmed/37430204
http://dx.doi.org/10.1186/s12864-023-09482-3