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CimpleG: finding simple CpG methylation signatures

DNA methylation signatures are usually based on multivariate approaches that require hundreds of sites for predictions. Here, we propose a computational framework named CimpleG for the detection of small CpG methylation signatures used for cell-type classification and deconvolution. We show that Cim...

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Detalles Bibliográficos
Autores principales: Maié, Tiago, Schmidt, Marco, Erz, Myriam, Wagner, Wolfgang, G. Costa, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332104/
https://www.ncbi.nlm.nih.gov/pubmed/37430364
http://dx.doi.org/10.1186/s13059-023-03000-0