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CimpleG: finding simple CpG methylation signatures
DNA methylation signatures are usually based on multivariate approaches that require hundreds of sites for predictions. Here, we propose a computational framework named CimpleG for the detection of small CpG methylation signatures used for cell-type classification and deconvolution. We show that Cim...
Autores principales: | Maié, Tiago, Schmidt, Marco, Erz, Myriam, Wagner, Wolfgang, G. Costa, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332104/ https://www.ncbi.nlm.nih.gov/pubmed/37430364 http://dx.doi.org/10.1186/s13059-023-03000-0 |
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