The role of irradiation in the management of the axilla in early breast cancer patients

The need for axillary radiotherapy in patients with invasive breast cancer (IBC) has been a topic of great debate in the last decade. Management of the axilla has evolved significantly over the past four decades with a trend towards de-escalation of surgical interventions and the aim of reducing mor...

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Autores principales: Elumalai, Thiraviyam, Jain, Urvashi, Coles, Charlotte E., Benson, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332143/
https://www.ncbi.nlm.nih.gov/pubmed/37434967
http://dx.doi.org/10.3389/fonc.2023.1151460
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author Elumalai, Thiraviyam
Jain, Urvashi
Coles, Charlotte E.
Benson, John R.
author_facet Elumalai, Thiraviyam
Jain, Urvashi
Coles, Charlotte E.
Benson, John R.
author_sort Elumalai, Thiraviyam
collection PubMed
description The need for axillary radiotherapy in patients with invasive breast cancer (IBC) has been a topic of great debate in the last decade. Management of the axilla has evolved significantly over the past four decades with a trend towards de-escalation of surgical interventions and the aim of reducing morbidity and enhancing QOL without compromising long-term oncology outcomes. This review article will address the role of axillary irradiation with a focus on the omission of completion axillary lymph node dissection in selected patients with sentinel lymph node (SLN) positive early breast cancer (EBC) with reference to current guidelines based on evidence to date.
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spelling pubmed-103321432023-07-11 The role of irradiation in the management of the axilla in early breast cancer patients Elumalai, Thiraviyam Jain, Urvashi Coles, Charlotte E. Benson, John R. Front Oncol Oncology The need for axillary radiotherapy in patients with invasive breast cancer (IBC) has been a topic of great debate in the last decade. Management of the axilla has evolved significantly over the past four decades with a trend towards de-escalation of surgical interventions and the aim of reducing morbidity and enhancing QOL without compromising long-term oncology outcomes. This review article will address the role of axillary irradiation with a focus on the omission of completion axillary lymph node dissection in selected patients with sentinel lymph node (SLN) positive early breast cancer (EBC) with reference to current guidelines based on evidence to date. Frontiers Media S.A. 2023-06-26 /pmc/articles/PMC10332143/ /pubmed/37434967 http://dx.doi.org/10.3389/fonc.2023.1151460 Text en Copyright © 2023 Elumalai, Jain, Coles and Benson https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Elumalai, Thiraviyam
Jain, Urvashi
Coles, Charlotte E.
Benson, John R.
The role of irradiation in the management of the axilla in early breast cancer patients
title The role of irradiation in the management of the axilla in early breast cancer patients
title_full The role of irradiation in the management of the axilla in early breast cancer patients
title_fullStr The role of irradiation in the management of the axilla in early breast cancer patients
title_full_unstemmed The role of irradiation in the management of the axilla in early breast cancer patients
title_short The role of irradiation in the management of the axilla in early breast cancer patients
title_sort role of irradiation in the management of the axilla in early breast cancer patients
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332143/
https://www.ncbi.nlm.nih.gov/pubmed/37434967
http://dx.doi.org/10.3389/fonc.2023.1151460
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