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Pseudo-Thrombotic Thrombocytopenic Purpura Due to Severe Vitamin B12 Deficiency: A Case Report

Vitamin B12 deficiency is common in vegetarians, as meat is a common source of vitamin B12. In this case presentation, a patient presented to his primary care doctor with signs of severe vitamin B12 deficiency anemia. He had elevated lactate dehydrogenase levels, indirect bilirubin, and schistocytes...

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Detalles Bibliográficos
Autores principales: Sathi, Thanmay, Luhadia, Kunjal, Yashi, Kanica, Virk, Jaswinder, Parikh, Taral, Dogra, Megha, Alam, Ahmad S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332188/
https://www.ncbi.nlm.nih.gov/pubmed/37435279
http://dx.doi.org/10.7759/cureus.40212
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author Sathi, Thanmay
Luhadia, Kunjal
Yashi, Kanica
Virk, Jaswinder
Parikh, Taral
Dogra, Megha
Alam, Ahmad S
author_facet Sathi, Thanmay
Luhadia, Kunjal
Yashi, Kanica
Virk, Jaswinder
Parikh, Taral
Dogra, Megha
Alam, Ahmad S
author_sort Sathi, Thanmay
collection PubMed
description Vitamin B12 deficiency is common in vegetarians, as meat is a common source of vitamin B12. In this case presentation, a patient presented to his primary care doctor with signs of severe vitamin B12 deficiency anemia. He had elevated lactate dehydrogenase levels, indirect bilirubin, and schistocytes on the blood smear, all pointing toward a hemolytic process. A severe vitamin B12 deficiency was deemed the cause of this hemolytic anemia after ruling out other causes. We highlight the importance of knowing more about this pathogenesis to avoid unnecessary workup and management for an elementary disorder that can result from severe B12 deficiency.
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spelling pubmed-103321882023-07-11 Pseudo-Thrombotic Thrombocytopenic Purpura Due to Severe Vitamin B12 Deficiency: A Case Report Sathi, Thanmay Luhadia, Kunjal Yashi, Kanica Virk, Jaswinder Parikh, Taral Dogra, Megha Alam, Ahmad S Cureus Internal Medicine Vitamin B12 deficiency is common in vegetarians, as meat is a common source of vitamin B12. In this case presentation, a patient presented to his primary care doctor with signs of severe vitamin B12 deficiency anemia. He had elevated lactate dehydrogenase levels, indirect bilirubin, and schistocytes on the blood smear, all pointing toward a hemolytic process. A severe vitamin B12 deficiency was deemed the cause of this hemolytic anemia after ruling out other causes. We highlight the importance of knowing more about this pathogenesis to avoid unnecessary workup and management for an elementary disorder that can result from severe B12 deficiency. Cureus 2023-06-10 /pmc/articles/PMC10332188/ /pubmed/37435279 http://dx.doi.org/10.7759/cureus.40212 Text en Copyright © 2023, Sathi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Sathi, Thanmay
Luhadia, Kunjal
Yashi, Kanica
Virk, Jaswinder
Parikh, Taral
Dogra, Megha
Alam, Ahmad S
Pseudo-Thrombotic Thrombocytopenic Purpura Due to Severe Vitamin B12 Deficiency: A Case Report
title Pseudo-Thrombotic Thrombocytopenic Purpura Due to Severe Vitamin B12 Deficiency: A Case Report
title_full Pseudo-Thrombotic Thrombocytopenic Purpura Due to Severe Vitamin B12 Deficiency: A Case Report
title_fullStr Pseudo-Thrombotic Thrombocytopenic Purpura Due to Severe Vitamin B12 Deficiency: A Case Report
title_full_unstemmed Pseudo-Thrombotic Thrombocytopenic Purpura Due to Severe Vitamin B12 Deficiency: A Case Report
title_short Pseudo-Thrombotic Thrombocytopenic Purpura Due to Severe Vitamin B12 Deficiency: A Case Report
title_sort pseudo-thrombotic thrombocytopenic purpura due to severe vitamin b12 deficiency: a case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332188/
https://www.ncbi.nlm.nih.gov/pubmed/37435279
http://dx.doi.org/10.7759/cureus.40212
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