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IL-7 producing immunotherapy improves ex vivo T cell functions of immunosenescent patients, especially post hip fracture

Following acute stress such as trauma or sepsis, most of critically ill elderly patients become immunosuppressed and susceptible to secondary infections and enhanced mortality. We have developed a virus-based immunotherapy encoding human interleukin-7 (hIL-7) aiming at restoring both innate an adapt...

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Detalles Bibliográficos
Autores principales: Marton, Chrystel, Minaud, Alix, Coupet, Charles-Antoine, Chauvin, Manon, Dhiab, Jamila, Vallet, Hélène, Boddaert, Jacques, Kehrer, Nadine, Bastien, Bérangère, Inchauspe, Geneviève, Barraud, Luc, Sauce, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332238/
https://www.ncbi.nlm.nih.gov/pubmed/37417353
http://dx.doi.org/10.1080/21645515.2023.2232247