Cargando…

Expression of lymphoid structure-associated cytokine/chemokine gene transcripts in tumor and protein in serum are prognostic of melanoma patient outcomes

BACKGROUND: Proinflammatory chemokines/cytokines support development and maturation of tertiary lymphoid structures (TLS) within the tumor microenvironment (TME). In the current study, we sought to investigate the prognostic value of TLS-associated chemokines/cytokines (TLS-kines) expression levels...

Descripción completa

Detalles Bibliográficos
Autores principales:	Karapetyan, Lilit, AbuShukair, Hassan M., Li, Aofei, Knight, Andrew, Al Bzour, Ayah Nedal, MacFawn, Ian P., Thompson, Zachary J., Chen, Ann, Yang, Xi, Dadey, Rebekah, Karunamurthy, Arivarasan, De Stefano, Danielle Vargas, Sander, Cindy, Kunning, Sheryl R., Najjar, Yana G., Davar, Diwakar, Luke, Jason J., Gooding, William, Bruno, Tullia C., Kirkwood, John M., Storkus, Walter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332263/ https://www.ncbi.nlm.nih.gov/pubmed/37435077 http://dx.doi.org/10.3389/fimmu.2023.1171978

Ejemplares similares

Sentinel Lymph Node Gene Expression Signature Predicts Recurrence-Free Survival in Cutaneous Melanoma
por: Karapetyan, Lilit, et al.
Publicado: (2022)

Toll-Like Receptor 9 Agonists in Cancer
por: Karapetyan, Lilit, et al.
Publicado: (2020)

Genomic and Transcriptomic Predictors of Response to Immune Checkpoint Inhibitors in Melanoma Patients: A Machine Learning Approach
por: Ahmed, Yaman B., et al.
Publicado: (2022)

Metastatic Melanoma With Sebocyte-Like Melanocytes and Widespread Visceral Involvement
por: Chang, Li-Wei, et al.
Publicado: (2020)

Type I interferons and related pathways in cell senescence
por: Frisch, Steven M., et al.
Publicado: (2020)

Immunotherapy in Melanoma: Recent Advances and Future Directions
por: Knight, Andrew, et al.
Publicado: (2023)

A retrospective analysis of the impact of the COVID-19 pandemic on staging at presentation of patients with invasive melanoma
por: Shaikh, Saba S., et al.
Publicado: (2022)

Phase I trial of pembrolizumab plus vemurafenib and cobimetinib in patients with metastatic melanoma
por: Shaikh, Saba S., et al.
Publicado: (2022)

Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma
por: Augustin, Ryan C, et al.
Publicado: (2023)

Tumor cell p38 inhibition to overcome immunotherapy resistance
por: Luke, Jason J., et al.
Publicado: (2023)

Phialophora infection mimics pyogenic granuloma in a patient with a renal transplant
por: Derbyshire, Mark, et al.
Publicado: (2022)

Artificial Intelligence and Machine Learning Applications in Sudden Cardiac Arrest Prediction and Management: A Comprehensive Review
por: Aqel, Sarah, et al.
Publicado: (2023)

Improved prognosis and evidence of enhanced immunogenicity in tumor and circulation of high-risk melanoma patients with unknown primary
por: Tarhini, Ahmad A, et al.
Publicado: (2022)

Adjuvant Therapy: Melanoma
por: Davar, Diwakar, et al.
Publicado: (2011)

Immune-Related Adverse Events in PD-1 Treated Melanoma and Impact Upon Anti-Tumor Efficacy: A Real World Analysis
por: Bastacky, Melissa L., et al.
Publicado: (2021)

Enhanced immune activation within the tumor microenvironment and circulation of female high-risk melanoma patients and improved survival with adjuvant CTLA4 blockade compared to males
por: Saad, Mariam, et al.
Publicado: (2022)

Hydroxychloroquine‐induced repetitive atypical pustular drug eruptions in the same patient separated by 12 years
por: Chen, Jeffrey, et al.
Publicado: (2023)

Partial tumor irradiation plus pembrolizumab in treating large advanced solid tumor metastases
por: Korpics, Mark C., et al.
Publicado: (2023)

PD-1 Blockade in Advanced Melanoma in Patients with Hepatitis C and/or HIV
por: Davar, Diwakar, et al.
Publicado: (2015)

Intractable pruritic dermatosis of the perineum in a woman with highly unusual pathologic features
por: Mizes, Alicia, et al.
Publicado: (2022)

Cancer-Associated Fibroblasts in Gastrointestinal Cancers: Unveiling Their Dynamic Roles in the Tumor Microenvironment
por: Al-Bzour, Noor N., et al.
Publicado: (2023)

Metformin is associated with improved clinical outcomes in patients with melanoma: a retrospective, multi-institutional study
por: Augustin, Ryan C., et al.
Publicado: (2023)

Immune checkpoint blockade in triple negative breast cancer influenced by B cells through myeloid-derived suppressor cells
por: Vito, Alyssa, et al.
Publicado: (2021)

Metastatic Invasive Lobular Breast Cancer Presenting Clinically with Esophageal Dysphagia
por: Karapetyan, Lilit, et al.
Publicado: (2017)

Multiple primary melanoma in association with other personal and familial cancers
por: Yang, Xi, et al.
Publicado: (2022)

Sarcoidosis and Monoclonal Gammopathy of Undetermined Significance (MGUS): A True Association or Just a Coincidence?
por: Hassanein, Mohamed, et al.
Publicado: (2018)

Factors Affecting Patient Satisfaction with Complete Dentures
por: Oweis, Yara, et al.
Publicado: (2022)

MEK inhibitors for the treatment of NRAS mutant melanoma
por: Sarkisian, Saro, et al.
Publicado: (2018)

Targeting GITR in cancer immunotherapy – there is no perfect knowledge
por: Davar, Diwakar, et al.
Publicado: (2023)

Metastatic Sarcomatoid Squamous Cell Carcinoma of the Cervix Presenting with Chest Mass
por: Karapetyan, Lilit, et al.
Publicado: (2017)

High-dose interleukin-2 (HD IL-2) for advanced melanoma: a single center experience from the University of Pittsburgh Cancer Institute
por: Davar, Diwakar, et al.
Publicado: (2017)

Dendritic cell vaccines targeting tumor blood vessel antigens in combination with dasatinib induce therapeutic immune responses in patients with checkpoint-refractory advanced melanoma
por: Storkus, Walter J, et al.
Publicado: (2021)

Facts and Hopes for Gut Microbiota Interventions in Cancer Immunotherapy
por: Davar, Diwakar, et al.
Publicado: (2022)

Clinical Evaluation of an Off-the-Shelf Allogeneic Adipose Matrix for Soft Tissue Reconstruction
por: Kokai, Lauren E., et al.
Publicado: (2020)

Case Report: Single Dose Anti-PD1 in a Patient With Metastatic Melanoma and Cardiac Allograft
por: Goodman, Amy E., et al.
Publicado: (2021)

Injectable Allograft Adipose Matrix Supports Adipogenic Tissue Remodeling in the Nude Mouse and Human
por: Kokai, Lauren E., et al.
Publicado: (2019)

Regulatory T Cell–Derived TRAIL Is Not Required for Peripheral Tolerance
por: Dadey, Rebekah E., et al.
Publicado: (2021)

Dasatinib promotes the expansion of a therapeutically superior T-cell repertoire in response to dendritic cell vaccination against melanoma
por: Lowe, Devin B, et al.
Publicado: (2014)

Search for effective treatments in patients with advanced refractory melanoma continues: can novel intratumoral therapies deliver?
por: Najjar, Yana G
Publicado: (2021)

Near complete response after single dose of nivolumab in patient with advanced heavily pre-treated KRAS mutant pulmonary adenocarcinoma
por: Davar, Diwakar, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_th1bqplsr28afmi3md152440fn