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AATF/Che-1 RNA polymerase II binding protein overexpression reduces the anti-tumor NK-cell cytotoxicity through activating receptors modulation

INTRODUCTION: AATF/Che-1 over-expression in different tumors is well known and its effect on tumorigenicity is mainly due to its central role demonstrated in the oncogenic pathways of solid tumors, where it controls proliferation and viability. The effect exerted by tumors overexpressing Che-1 on th...

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Detalles Bibliográficos
Autores principales: Caforio, Matteo, Tumino, Nicola, Sorino, Cristina, Manni, Isabella, Di Giovenale, Stefano, Piaggio, Giulia, Iezzi, Simona, Strimpakos, Georgios, Mattei, Elisabetta, Moretta, Lorenzo, Fanciulli, M., Vacca, Paola, Locatelli, Franco, Folgiero, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332273/
https://www.ncbi.nlm.nih.gov/pubmed/37435061
http://dx.doi.org/10.3389/fimmu.2023.1191908