Cargando…
AATF/Che-1 RNA polymerase II binding protein overexpression reduces the anti-tumor NK-cell cytotoxicity through activating receptors modulation
INTRODUCTION: AATF/Che-1 over-expression in different tumors is well known and its effect on tumorigenicity is mainly due to its central role demonstrated in the oncogenic pathways of solid tumors, where it controls proliferation and viability. The effect exerted by tumors overexpressing Che-1 on th...
Autores principales: | Caforio, Matteo, Tumino, Nicola, Sorino, Cristina, Manni, Isabella, Di Giovenale, Stefano, Piaggio, Giulia, Iezzi, Simona, Strimpakos, Georgios, Mattei, Elisabetta, Moretta, Lorenzo, Fanciulli, M., Vacca, Paola, Locatelli, Franco, Folgiero, Valentina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10332273/ https://www.ncbi.nlm.nih.gov/pubmed/37435061 http://dx.doi.org/10.3389/fimmu.2023.1191908 |
Ejemplares similares
-
Che-1/AATF binds to RNA polymerase I machinery and sustains ribosomal RNA gene transcription
por: Sorino, Cristina, et al.
Publicado: (2020) -
CK2-mediated phosphorylation of Che-1/AATF is required for its pro-proliferative activity
por: Catena, Valeria, et al.
Publicado: (2021) -
Discovering Che-1/AATF: a new attractive target for cancer therapy
por: Iezzi, Simona, et al.
Publicado: (2015) -
HIPK2 sustains apoptotic response by phosphorylating Che-1/AATF and promoting its degradation
por: De Nicola, F, et al.
Publicado: (2014) -
Che-1/AATF: A Critical Cofactor for Both Wild-Type- and Mutant-p53 Proteins
por: Bruno, Tiziana, et al.
Publicado: (2016)